I’m concerned that spironolactone can cause birth defects. If I want to become pregnant in the future, how long should I stop the medication before trying?

Spironolactone may affect the sexual development of a male fetus and should not be taken if pregnant or trying to conceive. You should stop spironolactone before trying to conceive but there is no necessary waiting period. Spironolactone does not affect your ability to get pregnant. There are no long term effects on reproduction.