What can I expect with Spironolactone?

Spironolactone is a potassium sparing diuretic used to treat hormonal acne in women. Oral spironolactone cannot be prescribed to female patients (cis- or transgender) over the age of 45 or to any male patient (cis- or transgender) on Apostrophe. Spironolactone is a medication that acts on androgens, or male hormones, in the female body. By blocking the effect of acne-causing androgens, spironolactone can be very helpful for hormonal acne after 2-3 months of consistent use. Topical medications are often prescribed with spironolactone (and we even offer a topical spironolactone treatment).

Common side effects include breast tenderness, mild headaches, irritability, fatigue, menstrual spotting or irregularity, heavier periods, stomach upset, decreased libido and breast enlargement. Most mild side effects tend to improve with time.

Spironolactone can cause dizziness or lightheadedness if you become dehydrated. Increasing your fluid intake can help prevent dehydration. It's important to get up slowly if you have been seated or lying down for a long time.

Spironolactone can cause spotting or menstrual irregularities at higher doses. A birth control pill can help to regulate periods.